Publications
Ralph A. Bradshaw: Scholar, leader, entrepreneur, Stahl, P.D. (2022), Ralph A. Bradshaw: Scholar, leader, entrepreneur. FASEB BioAdvances, 4: 691-693.
Cost Burden of Endothelial Keratoplasty in Fuchs Endothelial Dystrophy: Real-World Analysis of a Commercially Insured US Population (2014–2019), Deepinder K Dhaliwal, Viktor Chirikov, Jordana Schmier, Sanika Rege, Schalon Newton Dovepress (2022)
Proliferation of Human Corneal Endothelia in Organ Culture Stimulated by Wounding and the Engineered Human Fibroblast Growth Factor 1 Derivative TTHX1114, David Eveleth, Sarah Pizzuto, Jessica Weant, Jennifer Jenkins-Eveleth, and Ralph A. Bradshaw Journal of Ocular Pharmacology and Therapeutics Ahead of Print (2020)
A Bell-Shaped Dose Response of Topical FGF-1 in Dermal Wound Healing of Aged Female BALB/cByJ Mice, Hagerott, B.N., Blumstein, A.J., McGarry, L.E., Cohen, H.M., Tenorio, C.A., Powell, B.D., Nagy, T. and Blaber, M. Journal of Proteins and Proteomics (2020)
Fine-sampled Photographic Quantitation of Dermal Wound Healing Senescence in Aged BALB/cByJ Mice and Therapeutic Intervention with FGF-1, Mellers, A., Tenorio, C.A., Lacatusu, D., Powell, B., Patel, B., Harper, K.M. and Blaber, M. Advances in Wound Care 7, 409-418 (2018)
Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "2nd Generation" Therapeutic Application, Xia, X., Kumru, O.S., Blaber, S.I., Middaugh, C.R., Li, L., Ornitz, D.M., Sutherland, M.A., Tenorio, C. and Blaber, M., J. Pharm. Sci. 105, 1444-53 (2016)
Accelerated healing in NONcNZO10/LtJ type 2 diabetic mice by FGF 1, Blaber, S.I., Diaz, J. and Blaber, M. Blaber et al., Wound Repair and Regeneration 23, 538-549 (2015)
Mutation Choice to Eliminate Buried Free Cysteines in Protein Therapeutics, Xia, X., Longo, L.M. and Blaber, M. J. Pharm. Sci. 104, 566–576 (2015) PMID: 25312595
Pharmacokinetic properties of 2nd-generation fibroblast growth factor-1 mutants for therapeutic application, Xia, X., Babcock, J.P., Blaber, S.I., Harper, K.M. and Blaber, M., PLoS ONE 7(11): e48210 (2012) PMID: 23133616
An empirical phase diagram approach to investigate conformational stability of "second-generation" functional mutants of acidic fibroblast growth factor (FGF-1), Alsenaidy, M.A., Wang, T., Kim, J.H., Joshi, S.B., Lee, J., Blaber, M., Volkin, D.B., and Middaugh, C.R., Prot. Sci. 21, 418-432 (2012) PMID: 221139
Increased Functional Half-life of Fibroblast Growth Factor-1 by Recovering a Vestigial Disulfide Bond, Lee, J. and Blaber, M., J. Proteins Proteomics, 1, 37-42 (2010)
The Interaction between Thermodynamic Stability and Buried Free Cysteines in Regulating the Functional Half-life of Fibroblast Growth Factor-1, Lee, J. and Blaber, M., J. Mol. Biol. 393, 113-127 (2009) PMID: 19695265
Structural Basis of Conserved Cysteine in the Fibroblast Growth Factor Family: Evidence for a Vestigial Half-cystine, Lee, J. and Blaber, M., J. Mol. Biol. 393, 128-139 (2009)
Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N- and C-terminus β-strand Interactions, Dubey, V.K., Lee, J., Somasundaram, T., Blaber, S. and Blaber, M., J. Mol. Biol. 371, 256-268 (2007)
An Atomic Resolution Structure for Human Fibroblast Growth Factor-1, Bernett, M.J., Somasundaram, T. and Blaber, M. Proteins: Structure, Function and Bioinformatics 57, 626-634 (2004)
Thermodynamic Characterization of Mutants of Human FGF-1 with an Increased Physiological Half-life, Culajay, J.F., Blaber, S.I., Khurana, A. and Blaber, M. Biochemistry 39, 7153-7158 (2000)
Reversible Thermal Denaturation of Human FGF-1 Induced by Low Concentrations of Guanidine Hydrochloride, Blaber, S.I., Culajay, J.F., Khurana, A. and Blaber, M. Biophysical Journal 77, 470-477 (1999)
X-ray Crystal Structure of Human Acidic Fibroblast Growth Factor, Blaber, M., DiSalvo, J. and Thomas, K.A. Biochemistry 35, 2086-2094 (1996)